Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-9-18
pubmed:abstractText
Disease processes that produce ischaemia are a common cause of morbidity and mortality in companion animals. The majority of damage to transiently ischaemia tissues occurs following reperfusion and not during ischaemia per se. This discovery raises the encouraging prospect that therapeutic intervention prior to reperfusion may reduce the severity of ischaemic damage. Recently, the central role of oxygen-derived free radicals (oxyradicals) in reperfusion injury has been demonstrated. It appears that the adverse consequences of ischaemic diseases can be reduced by optimizing the anti-oxidant capability of tissues with anti-oxidant nutrients or drugs. The importance of oxyradicals in individual ischaemic diseases of the dog and cat, however, remains largely uninvestigated. Similarly, the best pharmaceutical and nutritional approaches to the therapy of oxyradical-mediated damage have yet to be devised.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0007-1935
pubmed:author
pubmed:issnType
Print
pubmed:volume
151
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-98
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Ischaemia-reperfusion injury--a small animal perspective.
pubmed:affiliation
Department of Veterinary Clinical Sciences, Massey University, Palmerston North, New Zealand.
pubmed:publicationType
Journal Article, Review