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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1995-9-13
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pubmed:abstractText |
We have previously reported that the antecedent administration of glucocorticoids altered both the hormonal and proinflammatory cytokine responses to lipopolysaccharide (LPS) when administered to human volunteers. In that study, subjects with vastly exaggerated levels of tumor necrosis factor (TNF) and interleukin (IL)-6 12 and 144 hours after cortisol infusion exhibited hemodynamic and hormonal responses no different from those of untreated subjects after endotoxin. The current study examined levels of the antiinflammatory cytokines interleukin-1 receptor antagonist (IL-1ra) and soluble receptors to tumor necrosis factor (sTNF-R) in the same setting of the previous report.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0039-6060
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
406-10; discussion 410-1
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:7638758-Adult,
pubmed-meshheading:7638758-Blood,
pubmed-meshheading:7638758-Endotoxins,
pubmed-meshheading:7638758-Humans,
pubmed-meshheading:7638758-Hydrocortisone,
pubmed-meshheading:7638758-Lipopolysaccharides,
pubmed-meshheading:7638758-Receptors, Interleukin-1,
pubmed-meshheading:7638758-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:7638758-Solubility,
pubmed-meshheading:7638758-Time Factors,
pubmed-meshheading:7638758-Tumor Necrosis Factor-alpha
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pubmed:year |
1995
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pubmed:articleTitle |
Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings.
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pubmed:affiliation |
Department of Surgery, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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