| pubmed-article:7636861 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7636861 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:7636861 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:7636861 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:7636861 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:7636861 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:7636861 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:7636861 | pubmed:dateCreated | 1995-9-12 | lld:pubmed |
| pubmed-article:7636861 | pubmed:abstractText | The synthesis and sigma 1 and sigma 2 binding properties of several 1'- and 3'-halo- and 1',3'-dihalo-substituted analogues of (+)-N-benzyl- and (+)- and (-)-N-dimethylallyl-N-normetazocine are presented. Structure-activity relationship analyses of the binding data showed that halogen substitution at the 1'-position of these N-substituted N-normetazocine analogues had little effect on sigma 1 binding affinity, whereas 3'-halo substitution as well as 1',3'-dihalo substitution resulted in a reduction of affinity. sigma 2 affinity was increased by the presence of a 3'-bromo substituent in this series of (+)-N-substituted N-normetazocines. | lld:pubmed |
| pubmed-article:7636861 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7636861 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7636861 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7636861 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7636861 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:WilliamsWW | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:BowerW HWH | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:CarrollF IFI | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:BarAA | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:ZhangXX | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:MascarellaS... | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:Danso-Danquah... | lld:pubmed |
| pubmed-article:7636861 | pubmed:author | pubmed-author:SineBB | lld:pubmed |
| pubmed-article:7636861 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7636861 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:7636861 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:7636861 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7636861 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7636861 | pubmed:pagination | 2986-9 | lld:pubmed |
| pubmed-article:7636861 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:meshHeading | pubmed-meshheading:7636861-... | lld:pubmed |
| pubmed-article:7636861 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7636861 | pubmed:articleTitle | Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues. | lld:pubmed |
| pubmed-article:7636861 | pubmed:affiliation | Research Triangle Institute, Research Triangle Park, North Carolina 27709, USA. | lld:pubmed |
| pubmed-article:7636861 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7636861 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:7636861 | lld:chembl |
