Linked Life Data

7634678

Source:http://linkedlifedata.com/resource/pubmed/id/7634678

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
315
pubmed:dateCreated
1995-9-13
pubmed:abstractText
Retinoblastoma is the most common malignant intraocular neoplasm of childhood. Distant metastases to bone and bone marrow occur. The authors report on a retinoblastoma patient with metastases to the extraaxial skeleton. Implications for the orthopaedic surgeon and alternative diagnostic modalities are discussed. The case presented here exemplifies the potential role for the orthopaedic surgeon in making such a diagnosis in a child previously treated for retinoblastoma. Secondary nonocular malignant tumors should be considered in the differential diagnosis of patients with a history of retinoblastoma who have a painful extremity. Radiation treatment of the primary tumor increases the risk for nonocular secondary neoplasms. The structural alterations in the retinoblastoma gene in patients with osteosarcomas and the possible role of the retinoblastoma gene in the origin of osteosarcomas are also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0009-921X
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
251-6
pubmed:dateRevised
2005-3-3
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Metastatic retinoblastoma. Recent progress of interest to orthopaedic surgeons.
pubmed:affiliation
Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, USA.
pubmed:publicationType
Journal Article, Case Reports