Linked Life Data

7634299

Source:http://linkedlifedata.com/resource/pubmed/id/7634299

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12 Suppl 1
pubmed:dateCreated
1995-9-14
pubmed:abstractText
Left ventricular hypertrophy is accompanied by the remodeling of the collagen network. We have studied collagen network in left ventricular hypertrophy secondary to aortic stenosis by cardiac catheterization and endomyocardial biopsies. We have demonstrated that collagen architecture is abnormal in 2/3 of patients with aortic stenosis and is more important than collagen concentration in influencing myocardial stiffness and ejection fraction. Furthermore, we observed that relaxation and asynchrony were influenced by the degree of hypertrophy instead of by the collagen network. The postoperative regression of left ventricular hypertrophy and the changes in interstitial tissue after valve replacement have been studied in a subgroup of patients. The major finding is that the regression of myocardial hypertrophy is a process that occurs over many years after correction of primary hemodynamic abnormality. Six to 7 years after valve replacement we observed, together with the normalization of diastolic stiffness, the complete normalization of interstitial fibrosis that was primarily increased (both pre and early postoperatively).
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0393-1978
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Interstitial changes and ventricular hypertrophy in man].
pubmed:affiliation
Cattedra di Cardiologia, Università degli Studi Federico II, Napoli.
pubmed:publicationType
Journal Article, English Abstract