Linked Life Data

7633764

Source:http://linkedlifedata.com/resource/pubmed/id/7633764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-9-12
pubmed:abstractText
Conventional laser-Doppler perfusion measurements can only obtain information from a single site. Since superficial blood flow is heterogeneous, this is a serious limitation, particularly in studies of methods to improve skin flap survival. A scanning laser-Doppler instrument has been developed which provides both an image and quantitative information about perfusion of the superficial tissue. We have evaluated this instrument in a circumflex iliac artery island flap model in the pig. The validity of the model was demonstrated by fluorescein dye injection and histology. Elevation of flaps was found to increase proximal flap blood flow but to decrease it in the distal portion. In flaps subjected to arterial ischaemia (9 h) and reperfusion we found an early increase in proximal flow, which gradually extended distally over the first 40 to 60 min. 16 h later, flow had declined, compatible with reperfusion damage to the vasculature. We suggest that perfusion imaging may be a valuable technique for investigating the mechanisms and extent of reperfusion injury.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0007-1226
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
280-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Perfusion imaging of skin island flap blood flow by a scanning laser-Doppler technique.
pubmed:affiliation
Department of Dermatology, Churchill Hospital, Oxford, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't