Linked Life Data

7632421

Source:http://linkedlifedata.com/resource/pubmed/id/7632421

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-9-12
pubmed:abstractText
The sympathetic nervous system serves not only to regulate involuntary functions, but also appears to play an important part in modulating sensory processing. While studies in animal models of neuropathic pain and clinical observations point to a role of the sympathetic nervous system in certain chronic pain states, the function of the sympathetics in postoperative pain and inflammation is debatable. Behavioural studies in rats point to a contribution of the sympathetic postganglionic terminal in the hyperalgesia of cutaneous inflammation and the severity of arthritis. An indirect effect of noradrenaline and inflammatory mediators via the release of prostaglandins has been postulated. Neurophysiological studies of nociceptors in rats and psychophysical studies in humans have failed to provide confirmatory evidence for the role of the sympathetic efferents in inflammatory pain and hyperalgesia. The clinical significance of the potential interaction of the sympathetic nervous system and the somatic afferent system needs further investigation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0785-3890
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-6
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Role of the sympathetic nervous system in acute pain and inflammation.
pubmed:affiliation
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21281-5354, USA.
pubmed:publicationType
Journal Article, Review