Linked Life Data

76322

Source:http://linkedlifedata.com/resource/pubmed/id/76322

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1978-5-17
pubmed:abstractText
The field of human cytogenetics has expanded considerably in the past few years due, to a large extent, to the application of the metaphase banding techniques. Among many advances, the chromosomal abnormalities involved in over thirty newly discovered syndromes have been defined and consistent chromosome defects have been observed in several neoplasias. Very recent improvements in culture techniques through cell synchronization and in chromosome treatments, such as the use of minimal exposure to colcemid and/or the use of agents that inhibit chromosome condensation, allow for the routine utilization of highly elongated and finely banded prophase chromosomes. These new techniques are being used clinically to uncover previously undetectable chromosome defects, to localize the exact break points involved in numerous duplication-deficiencies known in man, and to establish possible phenotype-genotype relationships at a refined level.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0079-6174
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-88
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
High-resolution chromosome analysis in clinical medicine.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review