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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-9-5
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pubmed:databankReference | |
pubmed:abstractText |
The complete DNA sequence of a cosmid mapping to human Xq28 (DXS455) has been determined using a shotgun approach (genbank accession number: L31948). The cosmid insert is 38.4 kb in length, and contains several repetitive sequences, including a highly repetitive region located in a fragment previously shown to contain a polymorphic VNTR locus, as well as short di- and tri-nucleotide repeats. In addition to the previously known VNTR locus, a CA-repeat and an unusual 800-bp repetitive region have been found to be polymorphic. The repeated sequence mapping to the site of the VNTR locus spans 480 bp in the cosmid. In addition to several AT-dinucleotide stretches, this repeat has four copies of a 25 bp repeat unit and flanking sequences similar to this 25-mer. No expressed sequences have so far been identified in this cosmid.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1042-5179
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7626781-Bacteriophage M13,
pubmed-meshheading:7626781-Base Sequence,
pubmed-meshheading:7626781-Cosmids,
pubmed-meshheading:7626781-DNA,
pubmed-meshheading:7626781-Gene Library,
pubmed-meshheading:7626781-Genetic Markers,
pubmed-meshheading:7626781-Humans,
pubmed-meshheading:7626781-Minisatellite Repeats,
pubmed-meshheading:7626781-Molecular Sequence Data,
pubmed-meshheading:7626781-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:7626781-X Chromosome
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pubmed:year |
1995
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pubmed:articleTitle |
Complete sequence of a 38.4-kb human cosmid insert containing the polymorphic marker DXS455 from Xq28.
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pubmed:affiliation |
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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