pubmed-article:7626130 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0056371 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:7626130 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:7626130 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:7626130 | pubmed:dateCreated | 1995-8-25 | lld:pubmed |
pubmed-article:7626130 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7626130 | pubmed:abstractText | A polymerase chain reaction-generated mouse ACTH-R probe was used to screen a mouse genomic library, and a clone of 13kb containing the entire coding sequence was isolated. The coding sequence shows 84% homology with the human gene at the DNA level and encodes a peptide with 89% homology to the human ACTH-R. This gene is expressed as a major transcript of 1.8kb in the mouse adrenal gland. The gene was expressed in HeLa cells and cAMP production in response to either ACTH or alpha-MSH was measured. cAMP increased in an ACTH dose dependent manner suggesting an EC50 of 7 x 10(-10)M ACTH. alpha-MSH was without effect on this receptor. In conclusion we have cloned a mouse ACTH receptor gene and demonstrated for the first time its expression and functional effect in HeLa cells. | lld:pubmed |
pubmed-article:7626130 | pubmed:language | eng | lld:pubmed |
pubmed-article:7626130 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7626130 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7626130 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7626130 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7626130 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7626130 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7626130 | pubmed:month | Jul | lld:pubmed |
pubmed-article:7626130 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:7626130 | pubmed:author | pubmed-author:BarkerSS | lld:pubmed |
pubmed-article:7626130 | pubmed:author | pubmed-author:ClarkA JAJ | lld:pubmed |
pubmed-article:7626130 | pubmed:author | pubmed-author:KapasSS | lld:pubmed |
pubmed-article:7626130 | pubmed:author | pubmed-author:CammasF MFM | lld:pubmed |
pubmed-article:7626130 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7626130 | pubmed:day | 26 | lld:pubmed |
pubmed-article:7626130 | pubmed:volume | 212 | lld:pubmed |
pubmed-article:7626130 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7626130 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7626130 | pubmed:pagination | 912-8 | lld:pubmed |
pubmed-article:7626130 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:7626130 | pubmed:meshHeading | pubmed-meshheading:7626130-... | lld:pubmed |
pubmed-article:7626130 | pubmed:meshHeading | pubmed-meshheading:7626130-... | lld:pubmed |
pubmed-article:7626130 | pubmed:year | 1995 | lld:pubmed |
pubmed-article:7626130 | pubmed:articleTitle | Cloning, characterization and expression of a functional mouse ACTH receptor. | lld:pubmed |
pubmed-article:7626130 | pubmed:affiliation | Department of Chemical Endocrinology, St Bartholomew's Hospital Medical College, London, United Kingdom. | lld:pubmed |
pubmed-article:7626130 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7626130 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:7626130 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:17200 | entrezgene:pubmed | pubmed-article:7626130 | lld:entrezgene |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7626130 | lld:pubmed |