Linked Life Data

7625186

Source:http://linkedlifedata.com/resource/pubmed/id/7625186

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-8-31
pubmed:abstractText
As part of the US National Institute of Mental Health Collaborative Program on the Psychobiology of Depression study, a subset of 460 randomly chosen relatives of affectively ill probands were compared to a control group matched by the acquaintanceship method. The rate of major affective disorder in relatives was found to be 36%; the rate among controls was 28%. Relatives were also found to have significantly higher rates of bipolar II disorder, any Research Diagnostic Criteria (RDC) affective disorder and any RDC mental disorder. All of these rates were found to be significantly higher when female relatives were compared with their acquaintances, but only the rate of any RDC mental disorder was higher when this comparison was made in men. The acquaintanceship method enabled the selection of a control group that closely resembled the relatives, probably to the extent of "overmatching". When the match was evaluated to determine whether relatives tended to select comparably ill (or well) acquaintances, this was found to be the case only for alcoholic and never mentally ill relatives.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-690X
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
146-51
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Affective illness in family members and matched controls.
pubmed:affiliation
Washington University School of Medicine, Department of Psychiatry, St. Louis, MO 63110, USA.
pubmed:publicationType
Journal Article