Linked Life Data

7624625

Source:http://linkedlifedata.com/resource/pubmed/id/7624625

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1995-8-31
pubmed:abstractText
We have recently described a technique allowing routine integration of PET scan data in the planning of stereotactic brain biopsy [Levivier et al:, Neurosurgery, 1992; 31:792-797]. We now report our results in a consecutive series of 38 patients that underwent combined FDG-PET and CT-guided stereotactic biopsy between June 1991 and January 1993. Stereotactic procedures were performed according to a standard protocol in which two biopsy trajectories were used whenever possible. This yielded to a total of 78 trajectories. In 31 patients, at least 1 trajectory was defined using an abnormality visualized on PET. The histological diagnosis was obtained in all cases. The diagnostic yield of each trajectory according to the FDG uptake of PET and contrast enhancement on CT showed that most low-grade tumors were found in hypometabolic/hypodense areas, glioblastomas were all diagnosed in areas with increased FDG uptake and contrast enhancement on CT while data for anaplastic astrocytomas were heterogeneously distributed. In the present series, 6 targets defined on CT were nondiagnostic; this never occurred when targets were defined on FDG-PET. In one case of anaplastic astrocytoma, the diagnosis was only made using a target defined on PET in a normal CT area; the second trajectory was made in a contrast-enhanced area on CT and was nondiagnostic. Because only structural images such as CT or MRI are available preoperatively, we analyzed separately the benefit of FDG-PET-guided biopsy in patients who have either an enhanced- or a nonenhanced lesion on CT. CT-enhanced lesions were found in 27 patients.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1011-6125
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
144-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
PET in stereotactic conditions increases the diagnostic yield of brain biopsy.
pubmed:affiliation
Department of Neurosurgery, Université Libre de Bruxelles-Erasme Hospital, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't