Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7 Pt 2
pubmed:dateCreated
1995-8-30
pubmed:databankReference
pubmed:abstractText
A novel murine cDNA which encodes a protein designated neuropsin was cloned. Northern and in situ hybridization analyses demonstrated that neuropsin mRNA is expressed specifically in the limbic system of mouse brain and is localized at highest concentration in pyramidal neurons of the hippocampal CA1-3 subfields. Direct hippocampal stimulation and kindling induced by amygdaloid stimulation caused a significant bilateral change in neuropsin mRNA level in the hippocampal pyramidal neurons. The activity-dependent changes and the specific localization indicate that neuropsin is involved in hippocampal plasticity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0270-6474
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
5088-97
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:7623137-Amino Acid Sequence, pubmed-meshheading:7623137-Animals, pubmed-meshheading:7623137-Base Sequence, pubmed-meshheading:7623137-Blotting, Northern, pubmed-meshheading:7623137-Cloning, Molecular, pubmed-meshheading:7623137-DNA, Complementary, pubmed-meshheading:7623137-Electric Stimulation, pubmed-meshheading:7623137-Gene Expression, pubmed-meshheading:7623137-Hippocampus, pubmed-meshheading:7623137-Kallikreins, pubmed-meshheading:7623137-Kindling, Neurologic, pubmed-meshheading:7623137-Limbic System, pubmed-meshheading:7623137-Mice, pubmed-meshheading:7623137-Molecular Sequence Data, pubmed-meshheading:7623137-Polymerase Chain Reaction, pubmed-meshheading:7623137-RNA, Messenger, pubmed-meshheading:7623137-Serine Endopeptidases, pubmed-meshheading:7623137-Transcription, Genetic
pubmed:year
1995
pubmed:articleTitle
Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus.
pubmed:affiliation
Department of Structural Cellular Biology, Nara Institute of Science and Technology (NAIST), Japan.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't