Linked Life Data

7621772

Source:http://linkedlifedata.com/resource/pubmed/id/7621772

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-8-30
pubmed:abstractText
During presurgical evaluation event-related potentials were recorded with depth electrodes located longitudinally within the hippocampus in 25 patients suffering from unilateral temporal lobe epilepsy. Rare stimuli in a visual oddball paradigm elicited a pronounced negativity ("NO") in the hippocampal body. Amplitudes were significantly reduced on the side of the primary epileptogenic area. Visual presentations of words in a recognition paradigm evoked an earlier negativity ("ENW") in anterior and a later negativity ("LNW") in posterior hippocampal structures. Both were sensitive for recognition effects and showed reduced amplitudes on the side of the primary epileptogenic area. Relating the differences of left and right hippocampal "NO" and "ENW" amplitudes proved to be a sensitive method for topological diagnosis and allowed a correct lateralization of the primary epileptogenic area in all patients. Amplitudes of the hippocampal ENW, evoked in the dominant hemisphere by first presentations, strongly correlated with the recognition rate, when the primary epileptogenic area was situated in the contralateral temporal lobe. This correlation was reduced by the presence of ipsilateral epileptogenic foci.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0013-4694
pubmed:author
pubmed:issnType
Print
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-62
pubmed:dateRevised
2008-9-9
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Alterations of intrahippocampal cognitive potentials in temporal lobe epilepsy.
pubmed:affiliation
University Clinic of Epileptology, Bonn, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't