Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-8-31
|
pubmed:abstractText |
The purpose of this study was to determine the role of intestinal specific rotavirus IgA antibody in protection against diarrhoea due to rotavirus infection. Stool from children aged below 5 years with diarrhoea who reported to the Paediatric Observation Ward, Kenyatta National Hospital were examined for micro-organisms and IgA antibody. Specific rotavirus IgA antibody and antigen were determined using enzyme linked immunosorbent assay technique. Out of 153 stool specimens, 22% (34/153) were positive for rotavirus antigen and 15% (23/153) had IgA specific antibody to rotavirus. Children with specific IgA to rotavirus had no rotavirus except in two cases (p < 0.05). There was no difference in levels of specific IgA antibody between normal and malnourished children (p = 0.4). It is probable that intestinal specific IgA to rotavirus protects children against rotavirus diarrhoea.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0012-835X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
72
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
217-9
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:7621754-Antibodies, Viral,
pubmed-meshheading:7621754-Antigens, Viral,
pubmed-meshheading:7621754-Child, Preschool,
pubmed-meshheading:7621754-Child Nutrition Disorders,
pubmed-meshheading:7621754-Cross-Sectional Studies,
pubmed-meshheading:7621754-Diarrhea,
pubmed-meshheading:7621754-Feces,
pubmed-meshheading:7621754-Humans,
pubmed-meshheading:7621754-Immunoglobulin A,
pubmed-meshheading:7621754-Infant,
pubmed-meshheading:7621754-Intestinal Diseases,
pubmed-meshheading:7621754-Rotavirus,
pubmed-meshheading:7621754-Rotavirus Infections,
pubmed-meshheading:7621754-Severity of Illness Index,
pubmed-meshheading:7621754-Time Factors
|
pubmed:year |
1995
|
pubmed:articleTitle |
Association of human rotavirus infection and intestinal rotavirus-specific immunoglobulin A in children with diarrhoea.
|
pubmed:affiliation |
National Public Health Laboratory Service, Ministry of Health, Nairobi.
|
pubmed:publicationType |
Journal Article
|