Linked Life Data

7618427

Source:http://linkedlifedata.com/resource/pubmed/id/7618427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-8-24
pubmed:abstractText
In this multicenter double-blind randomized study the analgesic efficacy and safety of 50 mg tramadol was compared against 50 mg pentazocine by mouth in the treatment of 160 patients with acute pain following prolapsed intervertebral disc repair. The day of surgery patients were treated with parenteral opioids. The study started the morning after surgery. A wash out period of four hours was allowed after parenteral analgesics. Pain assessment was made using a visual analogue scale (VAS) and a verbal rating scale (VRS) during a six hours observation period. Remedication with the same drug at the same dosage was allowed if pain relief was unsatisfactory. Overall analgesic activity and spontaneously reported side effects were also registered. Results showed both treatments provided equivalent effective analgesia for the six hours observation period. The global assessment of analgesia by patient and observer was not significantly different for both treatments, although less additional medication was required in the pentazocine group. Side effects were quite common in both groups, and occurred more frequently in the pentazocine group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Efficacy and safety of oral tramadol and pentazocine for postoperative pain following prolapsed intervertebral disc repair.
pubmed:affiliation
St. Norbertus Hospital, Duffel.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Multicenter Study