Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-8-18
pubmed:abstractText
With the purpose of determining whether the risk of infection with a particular clone of Mycobacterium tuberculosis is influenced by the human immunodeficiency virus (HIV) status of the host, we analyzed and compared 68 mycobacterial isolates obtained from HIV-seropositive patients with tuberculosis (TB) in Dar es Salaam, Tanzania, with 66 mycobacterial isolates obtained from HIV-seronegative patients with TB in the same geographical region by using both DNA fingerprinting and classical phenotyping methods. One hundred one different IS6110 fingerprinting patterns were observed in the 134 isolates. The level of diversity of the DNA fingerprints observed in the HIV-seropositive group was comparable to the level of the diversity observed in the HIV-seronegative group. Resistance to a single anti-TB drug was found in 8.8% of the tested isolates, and 3.2% of the isolates were resistant to more than one anti-TB drug. The drug susceptibility profiles were not significantly difference between the two groups of isolates compared in the present study. Phenotypic characteristics which classify M. tuberculosis strains as belonging to the Asian subgroup correlated with a low IS6110 copy number per isolate. However, the occurrence of Asian subgroup strains was not associated with the HIV status of the patients. The results of the study suggested an equal risk of infection with a defined M. tuberculosis clone for HIV-seropositive and HIV-seronegative individuals.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1304721, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1345800, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1392824, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1475806, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1507374, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1518113, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1520806, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1573751, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1600578, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1616211, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1727901, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1928942, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-1968123, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-2915665, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-6146008, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-6146009, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-6299151, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-6621622, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-6813376, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-7883893, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-7910661, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-7993412, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-8096066, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-8098974, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-8104956, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-8324847, http://linkedlifedata.com/resource/pubmed/commentcorrection/7615706-8381814
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Africa, http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara, http://linkedlifedata.com/resource/pubmed/keyword/Correlation Studies, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/Diseases, http://linkedlifedata.com/resource/pubmed/keyword/Eastern Africa, http://linkedlifedata.com/resource/pubmed/keyword/English Speaking Africa, http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Genetic Technics, http://linkedlifedata.com/resource/pubmed/keyword/Hiv, http://linkedlifedata.com/resource/pubmed/keyword/Hiv Infections, http://linkedlifedata.com/resource/pubmed/keyword/Infections, http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Research Report, http://linkedlifedata.com/resource/pubmed/keyword/Statistical Studies, http://linkedlifedata.com/resource/pubmed/keyword/Studies, http://linkedlifedata.com/resource/pubmed/keyword/TANZANIA, http://linkedlifedata.com/resource/pubmed/keyword/TUBERCULOSIS, http://linkedlifedata.com/resource/pubmed/keyword/Viral Diseases
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
1064-9
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
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