Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
1995-8-24
pubmed:abstractText
Serum levels of interleukin (IL)-4, interferon (IFN)-gamma and soluble CD23 (sCD23) were analysed in a prospective study of 64 infants monitored from birth to 18 months of age. The levels were low at birth and then increased, reaching a peak at either 6 or 9 months and then decreased up to 18 months of age. The children who developed atopic disease during the first 18 months of life had significantly higher IL-4 median levels than those who did not. No relationship was seen between the levels of sCD23 and IFN-gamma and allergy. Thus, the IL-4 levels in serum, but not sCD23 and IFN-gamma, were associated with allergic disease in infancy. Elevated levels were recorded before the onset of clinical symptoms, indicating that atopic disease is associated with a primary deviation of T cell function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1018-2438
pubmed:author
pubmed:issnType
Print
pubmed:volume
107
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Interleukin-4, soluble CD23 and interferon-gamma levels in serum during the first 18 months of life.
pubmed:affiliation
Department of Paediatrics, University Hospital, Faculty of Health Sciences, Linköping University, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't