| pubmed-article:7612913 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7612913 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:7612913 | lifeskim:mentions | umls-concept:C0597250 | lld:lifeskim |
| pubmed-article:7612913 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:7612913 | lifeskim:mentions | umls-concept:C1706937 | lld:lifeskim |
| pubmed-article:7612913 | lifeskim:mentions | umls-concept:C0022840 | lld:lifeskim |
| pubmed-article:7612913 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7612913 | pubmed:dateCreated | 1995-8-18 | lld:pubmed |
| pubmed-article:7612913 | pubmed:abstractText | The placental transfer of D- and L-glucose was investigated in anaesthetised non-diabetic and streptozotocin-induced diabetic rats. Maternal to fetal transfer was determined by perfusing the fetal side of one placenta in situ whilst infusing a mixture of D-[3-3H]glucose and L-[1-14C]glucose into the maternal circulation. Back-transfer from the fetal to maternal circulation was assessed by determining the uptake of the radiolabelled glucoses from the perfusion fluid during a single passage through the placenta on the fetal side. Maternal diabetes resulted in a reduced utero-placental blood flow but an increased bidirectional transfer of D-glucose. Non-specific maternal to fetal placental transfer of L-glucose was greater in diabetic rats than in controls, and the loss of L-glucose during placental perfusion on the fetal side was, again, greater in diabetic than in control rats. This increased bidirectional 'leak' of glucose possibly reflects a functionally compromised placenta, caused by its formation in a diabetic milieu, and may explain the greater fetal-maternal glucose ratios found in diabetic rats relative to controls. | lld:pubmed |
| pubmed-article:7612913 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7612913 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7612913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7612913 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7612913 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:7612913 | pubmed:issn | 0940-5429 | lld:pubmed |
| pubmed-article:7612913 | pubmed:author | pubmed-author:ThomasC RCR | lld:pubmed |
| pubmed-article:7612913 | pubmed:author | pubmed-author:LowyCC | lld:pubmed |
| pubmed-article:7612913 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7612913 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:7612913 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7612913 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7612913 | pubmed:pagination | 23-7 | lld:pubmed |
| pubmed-article:7612913 | pubmed:dateRevised | 2009-9-29 | lld:pubmed |
| pubmed-article:7612913 | pubmed:meshHeading | pubmed-meshheading:7612913-... | lld:pubmed |
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| pubmed-article:7612913 | pubmed:meshHeading | pubmed-meshheading:7612913-... | lld:pubmed |
| pubmed-article:7612913 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7612913 | pubmed:articleTitle | Bidirectional placental transfer ('leak') of L-glucose in control and diabetic rats. | lld:pubmed |
| pubmed-article:7612913 | pubmed:affiliation | Division of Medicine, United Medical School of Guy's Hospital, London, UK. | lld:pubmed |
| pubmed-article:7612913 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7612913 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7612913 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
