Linked Life Data

7612065

Source:http://linkedlifedata.com/resource/pubmed/id/7612065

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-8-14
pubmed:abstractText
In this study some alpha-(1,2,4-triazolyl)acetophenone derivatives were synthesized by the condensation of various triazole and alpha-bromoacetophenone rings. The structures of the compounds have been elucidated by UV, IR, 1H-NMR, mass spectra and elementary analysis. The in vitro antifungal activity of the compounds were investigated against some yeast-like fungi (Candida albicans, C. parapsilosis, C. stellatoidea and C. pseudotropicalis) and moulds such as Trichophyton rubrum and T. mentagrophytes by the tube dilution method and MIC (minimal inhibitory concentration), MFC (minimal fungicidal concentration) values were determined. Compound A16 was significantly more effective than the other compounds. The results obtained for antifungal activity against moulds were not significant.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
620-3
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Synthesis and antifungal activities of some new triazolylacetophenone derivatives.
pubmed:affiliation
Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Turkey.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't