| pubmed-article:7608177 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7608177 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7608177 | lifeskim:mentions | umls-concept:C0034987 | lld:lifeskim |
| pubmed-article:7608177 | lifeskim:mentions | umls-concept:C1707134 | lld:lifeskim |
| pubmed-article:7608177 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:7608177 | lifeskim:mentions | umls-concept:C0949374 | lld:lifeskim |
| pubmed-article:7608177 | pubmed:issue | 27 | lld:pubmed |
| pubmed-article:7608177 | pubmed:dateCreated | 1995-8-16 | lld:pubmed |
| pubmed-article:7608177 | pubmed:abstractText | The B creatine kinase gene is regulated by an array of positive and negative cis-elements in the 5'-flanking DNA that function in both muscle and nonmuscle cells. In C2C12 myogenic cells M and B creatine kinase mRNAs are coordinately up-regulated in the early stages of myogenesis and then undergo distinct regulatory programs. The B creatine kinase gene is down-regulated in the late stages of myogenesis as M creatine kinase becomes the predominant species in mature myotubes. Sequences between -92 and +80 of the B creatine kinase gene confer a regulated pattern of expression to chimeric plasmids that closely resembles the time-course of expression of the endogenous B creatine kinase gene in C2C12 cells undergoing differentiation. We show that sequences within the first exon of the B creatine kinase gene are important for the development regulation of the gene in C2C12 cells and that these sequences bind a nuclear protein that shows a similar tissue-specific distribution and developmentally regulated expression to that of the endogenous B creatine kinase gene. | lld:pubmed |
| pubmed-article:7608177 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7608177 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7608177 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7608177 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7608177 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7608177 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7608177 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7608177 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7608177 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7608177 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:7608177 | pubmed:author | pubmed-author:ZhangJ NJN | lld:pubmed |
| pubmed-article:7608177 | pubmed:author | pubmed-author:BilladelloJ... | lld:pubmed |
| pubmed-article:7608177 | pubmed:author | pubmed-author:WilksJ EJE | lld:pubmed |
| pubmed-article:7608177 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7608177 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:7608177 | pubmed:volume | 270 | lld:pubmed |
| pubmed-article:7608177 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7608177 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7608177 | pubmed:pagination | 16134-9 | lld:pubmed |
| pubmed-article:7608177 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:meshHeading | pubmed-meshheading:7608177-... | lld:pubmed |
| pubmed-article:7608177 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7608177 | pubmed:articleTitle | Characterization of a nuclear protein that interacts with regulatory elements in the human B creatine kinase gene. | lld:pubmed |
| pubmed-article:7608177 | pubmed:affiliation | Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri 63110, USA. | lld:pubmed |
| pubmed-article:7608177 | pubmed:publicationType | Journal Article | lld:pubmed |
