Linked Life Data

7608049

Source:http://linkedlifedata.com/resource/pubmed/id/7608049

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-8-14
pubmed:abstractText
This article approaches the question of bipolarity in childhood and adolescence from an "adult" perspective. It argues that clinically ascertained juvenile depressions--with onsets typically in late childhood or early adolescence--have affinity to bipolar spectrum disorders based on (1) early age at onset; (2) even gender ratio; (3) prominence of irritability, labile moods, and explosive anger indicative of mixed episodes; (4) high rates of "comorbid" substance abuse; (5) questionable response to antidepressants and/or brief hypomanic switches; (6) high rates of recurrence; (7) familial affective loading; and (8) frequent superposition on affective temperamental dysregulation. Building on the last point, the author submits that dysthymic, cyclothymic, and hyperthymic temperaments represent putative developmental pathways to bipolarity (as contrasted to "inhibited" anxious-phobic types, which appear related to nonbipolar outcomes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0890-8567
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
754-63
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Developmental pathways to bipolarity: are juvenile-onset depressions pre-bipolar?
pubmed:affiliation
University of California at San Diego, La Jolla 92093-0603, USA.
pubmed:publicationType
Journal Article, Review