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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-8-16
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pubmed:abstractText |
The aim of this study was to evaluate the diagnostic value of technetium-99m hexamethylpropylene amine oxime leucocyte scintigraphy (HMPAO-LS) by means of a retrospective review of 116 patients divided into three groups of bone and joint infection. One hundred and thirty-one LS examinations were performed, and 143 sites analysed. The final diagnosis of infection was based on surgical, histological and bacteriological data and follow-up. Ninety-four suspected localizations were examined in group 1, which included 74 patients with an infection suspected to involve orthopaedic implants. In this group, there were 38 true-positives, 1 false-negative, 49 true-negatives and 6 false-positives. Surgical confirmation was obtained in 34 cases. In group 2 (24 patients with suspected osteomyelitis), there were 27 localizations of which 14 were true-positives and 13 were true-negatives (including seven surgical confirmations). In group 3 (18 patients suspected of septic arthritis) there were eight true-positives, two false-negatives, ten true-negatives and two false-positives. Overall sensitivity of 99mTc-HMPAO-LS for the detection of bone and joint infection was 95%, with a specificity of 90% (group 1: sensitivity 97%, specificity 89%; group 2: 100% and 100%; group 3: 80% and 83%). It may be concluded that HMPAO-LS is an effective tool for the diagnosis of both bone infection involving implants and chronic osteomyelitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0340-6997
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
302-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7607260-Arthritis, Infectious,
pubmed-meshheading:7607260-Case-Control Studies,
pubmed-meshheading:7607260-False Negative Reactions,
pubmed-meshheading:7607260-False Positive Reactions,
pubmed-meshheading:7607260-Humans,
pubmed-meshheading:7607260-Leukocytes,
pubmed-meshheading:7607260-Organotechnetium Compounds,
pubmed-meshheading:7607260-Osteomyelitis,
pubmed-meshheading:7607260-Oximes,
pubmed-meshheading:7607260-Prostheses and Implants,
pubmed-meshheading:7607260-Prosthesis-Related Infections,
pubmed-meshheading:7607260-Retrospective Studies,
pubmed-meshheading:7607260-Sensitivity and Specificity,
pubmed-meshheading:7607260-Technetium Tc 99m Exametazime
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pubmed:year |
1995
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pubmed:articleTitle |
Technetium-99m hexamethylpropylene amine oxime leucocyte scintigraphy for the diagnosis of bone and joint infections: a retrospective study in 116 patients.
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pubmed:affiliation |
Department of Nuclear Medicine, Centre Eugène Marquis, Rennes, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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