Linked Life Data

7603623

Source:http://linkedlifedata.com/resource/pubmed/id/7603623

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-8-10
pubmed:abstractText
Loss of neuronal plasticity and/or alterations in neuronal targets with ageing can induce degenerative phenomena in the nervous system. To study the possible contribution of reduced neuronal plasticity to age-related neurodegeneration, we examined the sprouting response to aged rat iridial nerves on in oculo grafts of peripheral tissues taken from young and old animals. Contrary to previous observations in young hosts, both young and old transplants became re-innervated by host nerves to a similar extent, with a nerve density which was typical of old target tissue in situ. Nerve growth factor treatment increased the innervation density on all transplants. However, the increase was significant only on young target tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-50
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Collateral sprouting and responsiveness to nerve growth factor of ageing neurons.
pubmed:affiliation
Department of Anatomy and Developmental Biology, Royal Free Hospital School of Medicine, London, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't