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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1995-8-10
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pubmed:abstractText |
Four bioactive peptides were purified from an extract of the polycheate annelid Perinereis vancaurica using an HPLC system for fractionation of the extract and the esophagus of the worm as bioassay system. The sequences of the peptides were determined to be H-Trp-Val-Val-Gly-Asp-Val-Gln-OH, H-Ala-Thr-Trp-Leu-Asp-Thr-OH, H-Trp-Met-Val-Gly-Asp-Val-Gln-OH and H-Phe-Tyr-Glu-Gly-Asp-Val-Pro-Tyr-OH. These peptides showed an excitatory activity on the esophagus of P. vancaurica. The excitatory effect of the second and fourth peptides was marked. They may be neuropeptides involved in regulation of the esophagus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1367-8280
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-304
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:7599979-Amino Acid Sequence,
pubmed-meshheading:7599979-Animals,
pubmed-meshheading:7599979-Biological Assay,
pubmed-meshheading:7599979-Chromatography, High Pressure Liquid,
pubmed-meshheading:7599979-Chromatography, Ion Exchange,
pubmed-meshheading:7599979-Dose-Response Relationship, Drug,
pubmed-meshheading:7599979-Esophagus,
pubmed-meshheading:7599979-Excitatory Amino Acids,
pubmed-meshheading:7599979-Molecular Sequence Data,
pubmed-meshheading:7599979-Muscles,
pubmed-meshheading:7599979-Neuropeptides,
pubmed-meshheading:7599979-Peptides,
pubmed-meshheading:7599979-Polychaeta
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pubmed:year |
1995
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pubmed:articleTitle |
Isolation and characterization of four novel bioactive peptides from a polychaete annelid, Perinereis vancaurica.
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pubmed:affiliation |
Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.
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pubmed:publicationType |
Journal Article
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