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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-8-7
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pubmed:abstractText |
To detect growth hormone-releasing hormone (GHRH) secreted by monodispersed human GH-producing pituitary adenoma cells, the cell immunoblot assay was performed. GHRH-secreting cells were observed in 3 cases of GH-producing pituitary adenomas. The incidence of GHRH-secreting cells in the total cell populations was 0.24-3.42%. By contrast, no GHRH-secreting cells were observed in 2 cases of clinically nonfunctioning pituitary adenomas. The findings obtained by immunohistochemical studies for adenohypophysial hormones and for nuclear antigens of proliferative activity revealed that the incidence of GHRH-secreting cells is more related to the frequency of GH cells than to the proliferative activity in GH-producing pituitary adenomas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0918-8959
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7599704-Adenoma,
pubmed-meshheading:7599704-Adult,
pubmed-meshheading:7599704-Female,
pubmed-meshheading:7599704-Growth Hormone,
pubmed-meshheading:7599704-Growth Hormone-Releasing Hormone,
pubmed-meshheading:7599704-Humans,
pubmed-meshheading:7599704-Immunoblotting,
pubmed-meshheading:7599704-Immunohistochemistry,
pubmed-meshheading:7599704-Male,
pubmed-meshheading:7599704-Middle Aged,
pubmed-meshheading:7599704-Pituitary Neoplasms
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pubmed:year |
1995
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pubmed:articleTitle |
Secretion of growth hormone (GH)-releasing hormone by GH-producing pituitary adenoma assessed by cell immunoblot analysis.
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pubmed:affiliation |
Department of Neurosurgery, Hiroshima University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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