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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-8-10
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pubmed:abstractText |
We succeeded in establishing a human gastric carcinoma cell line (KE-39) from oncocytes obtained from the primary focus of a 77-year-old male stomach cancer patient. From a histopathological point of view the gastric carcinoma was a poorly differentiated adenocarcinoma exhibiting a funicular from and a structure with a solid vesicular focus. The oncocytes adhered to glass and proliferated in cell clusters, with a doubling time of about 38.4 hours. Upon transplantation of the cancer cells into nude mice, no visible tumors were found, but from a histological point of view poorly differentiated adenocarcinoma similar to the primary focus was found in all cases. With immunological staining they were found to be positive for anti-CEA antibody and anti-CA19-9 antibody, but negative for anti-ICAM-1 antibody. KE-39 is a cell line which was established from the primary focus, and it was reported in the belief that it is a useful cell line, upon the investigation of its cancer metastasis mechanism and cytological characteristics.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0914-7470
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7599112-Adenocarcinoma,
pubmed-meshheading:7599112-Aged,
pubmed-meshheading:7599112-Animals,
pubmed-meshheading:7599112-CA-19-9 Antigen,
pubmed-meshheading:7599112-Carcinoembryonic Antigen,
pubmed-meshheading:7599112-Humans,
pubmed-meshheading:7599112-Male,
pubmed-meshheading:7599112-Mice,
pubmed-meshheading:7599112-Mice, Nude,
pubmed-meshheading:7599112-Neoplasm Transplantation,
pubmed-meshheading:7599112-Stomach Neoplasms,
pubmed-meshheading:7599112-Tumor Cells, Cultured,
pubmed-meshheading:7599112-Tumor Markers, Biological
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pubmed:year |
1994
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pubmed:articleTitle |
[Establishment and characterization of strain KE-39 derived from human gastric cancer].
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pubmed:affiliation |
Division of Surgical Pathology, East Hospital Kitasato University.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|