7596152

Source:http://linkedlifedata.com/resource/pubmed/id/7596152

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007589, umls-concept:C0007634, umls-concept:C0034693, umls-concept:C0034721, umls-concept:C0038556, umls-concept:C0205263, umls-concept:C1511938, umls-concept:C1516960, umls-concept:C1517631, umls-concept:C1555707, umls-concept:C1705851, umls-concept:C2752151, umls-concept:C2828366
pubmed:issue	6
pubmed:dateCreated	1995-8-3
pubmed:abstractText	The extracts from rat submandibular glands (SMGs) induced erythroid differentiation of K-562. The activity was non-dialysable and abolished by heat, trypsin or 2-mercaptoethanol. Follistatin, which neutralizes the erythroid differentiation factor (EDF), had no effects on this activity. Analysis by gel chromatography and polyacrylamide gel electrophoresis-isoelectric focussing showed that the characteristics of this substance were different from those of erythropoietin, TGF-beta 1, EDF, stem cell factor and insulin-like growth factor-1. These results suggest the presence of a novel substance in rat SMGs which induces erythroid differentiation of K-562.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7706787
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Benzidines, http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobins, http://linkedlifedata.com/resource/pubmed/chemical/Tissue Extracts, http://linkedlifedata.com/resource/pubmed/chemical/benzidine
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0145-2126
pubmed:author	pubmed-author:EtohYY, pubmed-author:MasuyamaAA, pubmed-author:MiuraYY, pubmed-author:SasakiHH, pubmed-author:SasakiRR, pubmed-author:YoshidaHH
pubmed:issnType	Print
pubmed:volume	19
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	397-405
pubmed:dateRevised	2004-11-17
pubmed:meshHeading	pubmed-meshheading:7596152-Animals, pubmed-meshheading:7596152-Benzidines, pubmed-meshheading:7596152-Cell Differentiation, pubmed-meshheading:7596152-Cell Division, pubmed-meshheading:7596152-Cytokines, pubmed-meshheading:7596152-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:7596152-Female, pubmed-meshheading:7596152-Hemoglobins, pubmed-meshheading:7596152-Humans, pubmed-meshheading:7596152-Isoelectric Focusing, pubmed-meshheading:7596152-Kinetics, pubmed-meshheading:7596152-Leukemia, Erythroblastic, Acute, pubmed-meshheading:7596152-Male, pubmed-meshheading:7596152-Mice, pubmed-meshheading:7596152-Mice, Inbred BALB C, pubmed-meshheading:7596152-Rats, pubmed-meshheading:7596152-Rats, Wistar, pubmed-meshheading:7596152-Submandibular Gland, pubmed-meshheading:7596152-Tissue Extracts, pubmed-meshheading:7596152-Tumor Cells, Cultured
pubmed:year	1995
pubmed:articleTitle	The extracts from rat submandibular glands induce the erythroid differentiation of K-562 cells.
pubmed:affiliation	Department of Internal Medicine, Jichi Medical School, Tochigi, Japan.
pubmed:publicationType	Journal Article