| pubmed-article:7596151 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0280141 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0002073 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C1835417 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0175668 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0205164 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C0205165 | lld:lifeskim |
| pubmed-article:7596151 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:7596151 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:7596151 | pubmed:dateCreated | 1995-8-3 | lld:pubmed |
| pubmed-article:7596151 | pubmed:abstractText | In this paper we describe a patient with bcr/abl positive acute undifferentiated leukemia (AUL) derived from acquired sideroblastic anemia secondary to ifosphamide treatment given for the preceding non-Hodgkin lymphoma of the lung. Cytogenetically, Philadelphia chromosome was not detected through the whole course in this patient, and multiple chromosomal abnormalities including 5q- and monosomy 7 were found at the stage of sideroblastic anemia. The reverse transcriptase-polymerase chain reaction (RT-PCR) analysis showed no bcr/abl fusion transcript at the diagnosis of malignant lymphoma. The mRNA encoding the major bcr/abl fusion protein then appeared in the stage of sideroblastic anemia. Finally, the mRNA encoding both major and minor bcr/abl was detected in the stage of AUL transformation. MLL gene rearrangement was not found by RT-PCR analysis at any stage of the disorder. These results may be direct evidence for the induction of the bcr/abl fusion gene by treatment with an alkylating agent (ifosphamide). | lld:pubmed |
| pubmed-article:7596151 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7596151 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7596151 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7596151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7596151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7596151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7596151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7596151 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7596151 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:7596151 | pubmed:issn | 0145-2126 | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:HattoriMM | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:TanakaMM | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:YamazakiYY | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:NakaharaYY | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:TsushitaKK | lld:pubmed |
| pubmed-article:7596151 | pubmed:author | pubmed-author:UtumiMM | lld:pubmed |
| pubmed-article:7596151 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7596151 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:7596151 | pubmed:geneSymbol | MLL | lld:pubmed |
| pubmed-article:7596151 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7596151 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7596151 | pubmed:pagination | 389-96 | lld:pubmed |
| pubmed-article:7596151 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:7596151 | pubmed:meshHeading | pubmed-meshheading:7596151-... | lld:pubmed |
| pubmed-article:7596151 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7596151 | pubmed:articleTitle | Detection of major and minor bcr/abl fusion gene transcripts in a patient with acute undifferentiated leukemia secondary to treatment with an alkylating agent. | lld:pubmed |
| pubmed-article:7596151 | pubmed:affiliation | Nagoya National Hospital, Hematological Disease Center, Japan. | lld:pubmed |
| pubmed-article:7596151 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7596151 | pubmed:publicationType | Case Reports | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7596151 | lld:pubmed |
