Linked Life Data

7594351

Source:http://linkedlifedata.com/resource/pubmed/id/7594351

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1995-12-12
pubmed:abstractText
Ninety-three patients with gastric ulcers larger than 10 mm in diameter were randomly divided into two groups. Seventy patients received lansoprazole 30 mg once daily and 23 patients received cimetidine 400 mg twice daily. Ulcer healing was assessed by measuring changes in the longitudinal diameter of the ulcer at 2, 4, and 8 weeks after the start of treatment. In the lansoprazole group, ulcer diameters became significantly smaller than those in the cimetidine group. In the lansoprazole group, ulcer diameters did not differ significantly between patients younger than 65 years of age and those 65 or older at the evaluation points. However, in the cimetidine group, ulcer diameters became much smaller in patients younger than 65 years of age than in older patients. These results suggest that the potent acid suppression afforded by lansoprazole led to effective healing of gastric ulcers even in elderly gastric ulcer patients with defective mucosal protection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0192-0790
pubmed:author
pubmed:issnType
Print
pubmed:volume
20 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S86-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Evaluation of gastric ulcer healing by lansoprazole by measurement of ulcer diameter.
pubmed:affiliation
Second Department of Internal Medicine, Kobe University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Controlled Clinical Trial