rdf:type |
|
lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0020852,
umls-concept:C0030920,
umls-concept:C0034196,
umls-concept:C0035020,
umls-concept:C0043240,
umls-concept:C0050940,
umls-concept:C0087111,
umls-concept:C0229671,
umls-concept:C0441889,
umls-concept:C1280500
|
pubmed:dateCreated |
1995-12-12
|
pubmed:abstractText |
In the present study, the effects of short-term treatment with lansoprazole on healing and recurrence of peptic ulcer were investigated. Complete healing (change to the S2 stage) after 3 or 4 weeks of treatment with lansoprazole was observed in 9.9% of gastric ulcers and 38.3% of duodenal ulcers. Complete healing was observed after 3 or 4 weeks of treatment with lansoprazole in gastric ulcers and was significantly related to the serum titer of IgG anti-Helicobacter pylori antibodies. This was not the case in duodenal ulcers. Complete healing after 6 or 8 weeks of treatment with lansoprazole was not dependent on serum levels of IgG anti-H. pylori antibodies. Short-term treatment by lansoprazole did not affect serum levels of IgG anti-H. pylori antibodies immediately after the end of lansoprazole treatment, but significantly reduced serum levels of IgG anti-H. pylori antibodies were found 9 months after treatment.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0192-0790
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
20 Suppl 2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
S75-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7594347-2-Pyridinylmethylsulfinylbenzimidazoles,
pubmed-meshheading:7594347-Adult,
pubmed-meshheading:7594347-Aged,
pubmed-meshheading:7594347-Aged, 80 and over,
pubmed-meshheading:7594347-Anti-Ulcer Agents,
pubmed-meshheading:7594347-Antibodies, Bacterial,
pubmed-meshheading:7594347-Duodenal Ulcer,
pubmed-meshheading:7594347-Female,
pubmed-meshheading:7594347-Helicobacter pylori,
pubmed-meshheading:7594347-Humans,
pubmed-meshheading:7594347-Immunoglobulin G,
pubmed-meshheading:7594347-Male,
pubmed-meshheading:7594347-Middle Aged,
pubmed-meshheading:7594347-Omeprazole,
pubmed-meshheading:7594347-Peptic Ulcer,
pubmed-meshheading:7594347-Proton Pumps,
pubmed-meshheading:7594347-Recurrence,
pubmed-meshheading:7594347-Stomach Ulcer
|
pubmed:year |
1995
|
pubmed:articleTitle |
The effect of lansoprazole treatment on the healing and relapse of peptic ulcer and serum levels of IgG anti-Helicobacter pylori antibody.
|
pubmed:affiliation |
Department of Gastroenterology, University of Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|