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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Pt 2
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pubmed:dateCreated |
1995-12-12
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pubmed:abstractText |
The Muir-Torre syndrome is an autosomal dominant genodermatosis characterized by the occurrence of one or more sebaceous gland tumors (either adenoma, epithelioma, or carcinoma) and a single malignant internal neoplasm. To date, 133 cases of Muir-Torre syndrome have been described. Colorectal (49%) and genitourinary (21%) carcinomas are the most common initial neoplasms. The case of a man with a history of recurrent ocular sebaceous carcinoma who subsequently had seminoma is described, and previously published reports of men with Muir-Torre syndrome and genitourinary tumors are discussed. Including this report, an associated genitourinary tumor was the initial malignant internal neoplasm in 11 men with Muir-Torre syndrome. The detection of a genitourinary neoplasm preceded diagnosis of the patient's Muir-Torre syndrome-associated sebaceous gland tumor in five patients (45%). All patients with sebaceous gland tumors of the type associated with Muir-Torre syndrome warrant consideration of Muir-Torre syndrome and appropriate workup to detect asymptomatic malignant visceral neoplasms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0190-9622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
909-12
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7593809-Adenocarcinoma, Sebaceous,
pubmed-meshheading:7593809-Adult,
pubmed-meshheading:7593809-Fatal Outcome,
pubmed-meshheading:7593809-Humans,
pubmed-meshheading:7593809-Lymphatic Metastasis,
pubmed-meshheading:7593809-Male,
pubmed-meshheading:7593809-Neoplasm Recurrence, Local,
pubmed-meshheading:7593809-Neoplasms, Multiple Primary,
pubmed-meshheading:7593809-Neoplastic Syndromes, Hereditary,
pubmed-meshheading:7593809-Sebaceous Gland Neoplasms,
pubmed-meshheading:7593809-Seminoma,
pubmed-meshheading:7593809-Syndrome,
pubmed-meshheading:7593809-Urogenital Neoplasms
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pubmed:year |
1995
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pubmed:articleTitle |
Genitourinary tumors in men with the Muir-Torre syndrome.
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pubmed:affiliation |
Department of Medicine, University of Colorado Medical School, Denver, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
|