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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1995-12-12
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pubmed:abstractText |
GERI-BP001 compounds, new inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT), were isolated from a culture broth of Aspergillus fumigatus F37 by acetone extraction, EtOAc extraction, SiO2 column chromatography, and reverse phase HPLC. GERI-BP001 M, A, and B inhibit ACAT activity in an enzyme assay system using rat liver microsomes by 50% at concentrations of 42, 94, and 40 microM, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
751-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7592016-Animals,
pubmed-meshheading:7592016-Aspergillus fumigatus,
pubmed-meshheading:7592016-Enzyme Inhibitors,
pubmed-meshheading:7592016-Fermentation,
pubmed-meshheading:7592016-Microbial Sensitivity Tests,
pubmed-meshheading:7592016-Microsomes, Liver,
pubmed-meshheading:7592016-Pyridines,
pubmed-meshheading:7592016-Rats,
pubmed-meshheading:7592016-Sesquiterpenes,
pubmed-meshheading:7592016-Sterol O-Acyltransferase
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pubmed:year |
1995
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pubmed:articleTitle |
GERI-BP001 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Aspergillus fumigatus F37. I. Production, isolation, and physico-chemical and biological properties.
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pubmed:affiliation |
Bioproducts Research Group, Korea Research Institute of Bioscience & Biotechnology, KIST, Taejon.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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