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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1995-11-30
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pubmed:abstractText |
Following median nerve stimulation, several monophasic peaks were recorded at the scalp in the 15-18 ms time range. Source analysis, using three different methods, modelled a source near the centre of the head with an orientation towards the activated hemisphere and a peak activity at 16 ms post stimulus. Magnetic recordings detected no signal in this time range, which confirmed a subcortical location of the source. From dipole localization it was not possible to assign the exact origin of the P16 source to either the subthalamic level or the thalamo-cortical radiation, because of the limited spatial resolution at the centre of the spherical head model. An estimate of the conduction velocity of the medial lemniscus pointed towards a subthalamic origin. The P16 source was preserved in two patients with a lesion of the thalamo-cortical radiation and the ventral thalamus. Further evidence for a subthalamic location of P16 was derived from the physical mechanisms generating far-field potentials.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
511-8
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7589302-Adult,
pubmed-meshheading:7589302-Cerebral Cortex,
pubmed-meshheading:7589302-Cerebrovascular Disorders,
pubmed-meshheading:7589302-Electric Stimulation,
pubmed-meshheading:7589302-Electroencephalography,
pubmed-meshheading:7589302-Electromagnetic Fields,
pubmed-meshheading:7589302-Evoked Potentials, Somatosensory,
pubmed-meshheading:7589302-Female,
pubmed-meshheading:7589302-Head,
pubmed-meshheading:7589302-Humans,
pubmed-meshheading:7589302-Male,
pubmed-meshheading:7589302-Median Nerve,
pubmed-meshheading:7589302-Middle Aged,
pubmed-meshheading:7589302-Models, Neurological,
pubmed-meshheading:7589302-Orientation,
pubmed-meshheading:7589302-Space Perception,
pubmed-meshheading:7589302-Thalamic Nuclei,
pubmed-meshheading:7589302-Tomography, X-Ray Computed
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pubmed:year |
1995
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pubmed:articleTitle |
Origin of P16 median nerve SEP component identified by dipole source analysis--subthalamic or within the thalamo-cortical radiation?
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pubmed:affiliation |
Philips Research Laboratories, Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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