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pubmed-article:7588958pubmed:dateCreated1995-12-15lld:pubmed
pubmed-article:7588958pubmed:abstractTextA pilot study was performed to determine the incidence of congenital hypothyroidism (CH) in Turkey and to build a model for nationwide screening. From December 1991 to December 1992, 30,097 newborns were screened for CH using a primary measurement of thyroid stimulating hormone in capillary blood on days 3-5 of life. Samples were obtained in collaboration with the ongoing nationwide phenylketonuria screening programme. Eleven cases of primary CH were detected giving the incidence of 1:2736. Recall rate was 2.3%. Replacement therapy with L-thyroxine was started after the confirmation of diagnosis. The median age at the initiation of replacement therapy was 23 days (range 7-35 days). CONCLUSION: The incidence of CH is notably higher in Turkey than reported in most other countries. Iodine deficiency and/or dyshormonogenesis might contribute to this high incidence. This result emphasizes the necessity of a nationwide screening programme.lld:pubmed
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pubmed-article:7588958pubmed:pagination614-6lld:pubmed
pubmed-article:7588958pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:7588958pubmed:year1995lld:pubmed
pubmed-article:7588958pubmed:articleTitleScreening for congenital hypothyroidism in Turkey.lld:pubmed
pubmed-article:7588958pubmed:affiliationHacettepe University, Department of Paediatric Endocrinology, Ankara, Turkey.lld:pubmed
pubmed-article:7588958pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7588958pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed