Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1995-12-20
|
pubmed:abstractText |
To define the clinical characteristics of multiple lung cancer (LC) associated with idiopathic pulmonary fibrosis (IPF), we reviewed 154 LC patients associated with IPF: 23 patients with synchronous multiple LC (IPF-multiple LC group) and 131 with single LC (IPF-single LC group), and these were compared with 4,931 patients with LC from 1975 to 1977 in Japan (whole LC group). In the IPF-single and IPF-multiple LC groups, most tumors were observed in male patients (91% and 96%), smokers (94% and 100%), and in peripheral regions of the lung (91% and 98%). The incidence of occurrence in the lower lobes, where a fibrotic shadow was prominent, was significantly higher in the IPF-LC groups (58% and 67%) than for the whole LC group (37%). The distribution of histologic types in the IPF-single LC group was similar to that of the whole LC group. However, the incidence of small cell carcinoma was significantly higher in the IPF-multiple LC group (33%) than for the IPF-single LC (14%) and whole LC (12%) groups. These results indicate that the features characteristic to synchronous multiple LC in patients with IPF are as follows: (1) male patients; (2) smokers; (3) small cell carcinoma histologic type; (4) lower lobes; and (5) peripheral type, all of which show a high rate of occurrence.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0012-3692
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
108
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1272-7
|
pubmed:dateRevised |
2005-11-16
|
pubmed:meshHeading |
pubmed-meshheading:7587428-Aged,
pubmed-meshheading:7587428-Carcinoma, Small Cell,
pubmed-meshheading:7587428-Female,
pubmed-meshheading:7587428-Humans,
pubmed-meshheading:7587428-Japan,
pubmed-meshheading:7587428-Lung Neoplasms,
pubmed-meshheading:7587428-Male,
pubmed-meshheading:7587428-Middle Aged,
pubmed-meshheading:7587428-Neoplasms, Multiple Primary,
pubmed-meshheading:7587428-Pulmonary Fibrosis,
pubmed-meshheading:7587428-Retrospective Studies,
pubmed-meshheading:7587428-Smoking
|
pubmed:year |
1995
|
pubmed:articleTitle |
Clinical characteristics of synchronous multiple lung cancer associated with idiopathic pulmonary fibrosis. A review of Japanese cases.
|
pubmed:affiliation |
First Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.
|
pubmed:publicationType |
Journal Article,
Review
|