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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1995-12-7
|
| pubmed:abstractText |
The influence of the Gyne-T 380S intrauterine contraceptive device (IUD) on menstrual blood loss (MBL) and iron status (hemoglobin, hematocrit, red cell count and indices, and serum ferritin) was evaluated. MBL was determined objectively by the alkaline hematin method in 18 women (mean age 37.1 +/- 1.6 yr, range 22-46 yr) before and 3, 6 and 12 months after insertion of a Gyne-T 380S IUD. MBL prior to IUD insertion was 59 +/- 8 ml and increased to 91 +/- 11 ml (p < 0.01) 3 months after insertion. MBL then remained largely unchanged during the remainder of the observation period (6 months, 94 +/- 12 ml; 12 months, 92 +/- 13 ml). The percentage increase in MBL at the respective measurement points ranged between 54 and 59% which is comparable with previous reports regarding the increase in MBL associated with the use of a copper IUD. There were no significant changes recorded in iron status parameters during the 12-month observation period following IUD insertion. Based on the results of the present study, women from developed countries apparently tolerate an increased MBL of approximately 55% without developing iron deficiency anemia. Iron stores were unchanged indicating an adequate adaptive increase in intestinal iron absorption.
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/ANEMIA,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Methods--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Developed Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Europe,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Hemic System,
http://linkedlifedata.com/resource/pubmed/keyword/Iud, Copper Releasing--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Iud--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Menstruation Disorders,
http://linkedlifedata.com/resource/pubmed/keyword/Northern Europe,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Prospective Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Research Report,
http://linkedlifedata.com/resource/pubmed/keyword/Risk Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Scandinavia,
http://linkedlifedata.com/resource/pubmed/keyword/Serum Iron Level,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Sweden
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0010-7824
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
52
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
175-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:otherAbstract |
PIP: Increased menstrual blood loss is a common side effect associated with IUD use; its extent varies, however, according to the type of IUD and size of its surface area. The present study investigated the influence of the Gyne-T 380S IUD on menstrual blood loss and, consequently, on iron stores in 18 women who presented to East Hospital in Goteborg, Sweden, for IUD insertion. The mean duration of menstruation increased significantly from 4.8 +or- 0.2 days before IUD insertion to 6.1 +or- 0.3 days after insertion. Mean menstrual blood loss, determined by the alkaline hematin method, was 59 +or- 8 ml before insertion, rose significantly to 91 +or- 11 ml 3 months after insertion, and remained around this level at 6 and 12 months post-insertion. The percentage increases in blood loss were 54%, 59%, and 56%, respectively, 3, 6, and 12 months post-insertion. No significant changes in iron status parameters (hemoglobin, hematocrit, red cell count and indices, and serum ferritin) were recorded during the 12-month study period, however. These findings indicate that women from developed countries can tolerate menstrual blood losses in the range of 55% without developing iron deficiency anemia, presumably through an adaptive increase in intestinal iron absorption. In developing countries, on the other hand, similar increases in menstrual blood loss could result in anemia due to a poorer dietary intake of iron and high parity.
|
| pubmed:meshHeading |
pubmed-meshheading:7587189-Adult,
pubmed-meshheading:7587189-Erythrocyte Indices,
pubmed-meshheading:7587189-Female,
pubmed-meshheading:7587189-Ferritins,
pubmed-meshheading:7587189-Hematocrit,
pubmed-meshheading:7587189-Hemoglobins,
pubmed-meshheading:7587189-Humans,
pubmed-meshheading:7587189-Intrauterine Devices, Copper,
pubmed-meshheading:7587189-Iron,
pubmed-meshheading:7587189-Menstruation,
pubmed-meshheading:7587189-Middle Aged,
pubmed-meshheading:7587189-Uterine Hemorrhage
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
The influence of the Gyne-T 380S IUD on menstrual blood loss and iron status.
|
| pubmed:affiliation |
Department of Obstetrics & Gynecology, East Hospital, Göteborg, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|