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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1995-12-28
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pubmed:abstractText |
After several days of loading, oral amiodarone, a class III antiarrhythmic, is highly effective in controlling ventricular tachyarrhythmias; however, the delay in onset of activity is not acceptable in patients with immediately life-threatening arrhythmias. Therefore, an intravenous form of therapy is advantageous. This study was designed to compare the safety and efficacy of a high and a low dose of intravenous amiodarone with bretylium, the only approved class III antiarrhythmic agent.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-7322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3255-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7586312-Aged,
pubmed-meshheading:7586312-Amiodarone,
pubmed-meshheading:7586312-Anti-Arrhythmia Agents,
pubmed-meshheading:7586312-Bretylium Tosylate,
pubmed-meshheading:7586312-Dose-Response Relationship, Drug,
pubmed-meshheading:7586312-Double-Blind Method,
pubmed-meshheading:7586312-Female,
pubmed-meshheading:7586312-Humans,
pubmed-meshheading:7586312-Infusions, Intravenous,
pubmed-meshheading:7586312-Male,
pubmed-meshheading:7586312-Middle Aged,
pubmed-meshheading:7586312-Recurrence,
pubmed-meshheading:7586312-Tachycardia, Ventricular,
pubmed-meshheading:7586312-Time Factors,
pubmed-meshheading:7586312-Ventricular Fibrillation
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pubmed:year |
1995
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pubmed:articleTitle |
Randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent, hemodynamically destabilizing ventricular tachycardia or fibrillation. The Intravenous Amiodarone Multicenter Investigators Group.
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pubmed:affiliation |
Lankenau Hospital and Medical Research Center, Wynnewood, PA 19096, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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