rdf:type |
|
lifeskim:mentions |
umls-concept:C0016601,
umls-concept:C0018338,
umls-concept:C0030352,
umls-concept:C0034493,
umls-concept:C0069477,
umls-concept:C0150312,
umls-concept:C0233494,
umls-concept:C0441889,
umls-concept:C0442805,
umls-concept:C0547047,
umls-concept:C1533157
|
pubmed:issue |
3
|
pubmed:dateCreated |
1995-12-26
|
pubmed:abstractText |
The purpose of the present investigation was to determine whether stimulation of the nitric oxide synthase pathway contributes to the muscarinic receptor-mediated elevation in cGMP levels and reversal of the positive inotropic response to the adenylyl cyclase activator forskolin in rabbit papillary muscles.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0008-6363
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
372-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7585828-Animals,
pubmed-meshheading:7585828-Arginine,
pubmed-meshheading:7585828-Carbachol,
pubmed-meshheading:7585828-Cyclic GMP,
pubmed-meshheading:7585828-Female,
pubmed-meshheading:7585828-Forskolin,
pubmed-meshheading:7585828-Guanylate Cyclase,
pubmed-meshheading:7585828-Male,
pubmed-meshheading:7585828-Muscarinic Agonists,
pubmed-meshheading:7585828-Myocardial Contraction,
pubmed-meshheading:7585828-Nitric Oxide,
pubmed-meshheading:7585828-Nitroprusside,
pubmed-meshheading:7585828-Papillary Muscles,
pubmed-meshheading:7585828-Rabbits,
pubmed-meshheading:7585828-omega-N-Methylarginine
|
pubmed:year |
1995
|
pubmed:articleTitle |
L-NMMA blocks carbachol-induced increases in cGMP levels but not decreases in tension in the presence of forskolin in rabbit papillary muscles.
|
pubmed:affiliation |
Division of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|