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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1995-12-4
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pubmed:abstractText |
A cDNA library was constructed from liver RNA of the Australian diprotodont marsupial Macropus eugenii, the Tammar wallaby. A cloned full-length transthyretin cDNA was sequenced. The derived amino-acid sequence showed 68% overall similarity to that of human transthyretin, with 86% similarity in the thyroxine binding site. Comparisons of nucleotide and amino acid sequences from several vertebrate species indicated that the greatest differences were in the region corresponding to the disordered N-terminus of mature human transthyretin. The evolutionary trees deduced from parsimony analyses of amino acid and nucleotide sequences of transthyretins, are consistent with that derived from fossil records.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1096-4959
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
523-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7584829-Amino Acid Sequence,
pubmed-meshheading:7584829-Animals,
pubmed-meshheading:7584829-Base Sequence,
pubmed-meshheading:7584829-Cloning, Molecular,
pubmed-meshheading:7584829-DNA, Complementary,
pubmed-meshheading:7584829-Humans,
pubmed-meshheading:7584829-Liver,
pubmed-meshheading:7584829-Macropodidae,
pubmed-meshheading:7584829-Molecular Sequence Data,
pubmed-meshheading:7584829-Phylogeny,
pubmed-meshheading:7584829-Prealbumin,
pubmed-meshheading:7584829-Sequence Homology, Amino Acid,
pubmed-meshheading:7584829-Sequence Homology, Nucleic Acid,
pubmed-meshheading:7584829-Species Specificity
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pubmed:year |
1995
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pubmed:articleTitle |
Wallaby transthyretin.
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pubmed:affiliation |
Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, Australia.
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pubmed:publicationType |
Journal Article,
Comparative Study
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