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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1995-12-15
|
| pubmed:abstractText |
Laboratory studies suggest that the postischaemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure. Platelet-activating factor, generated by phospholipase A2, appears to be active in priming neutrophils in the gut. Interleukin-6 also appears to be elaborated by the postischaemic gut, but may be even more important in distant organs via promoting neutrophil-mediated organ dysfunction.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0007-1064
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
134-8
|
| pubmed:dateRevised |
2005-11-16
|
| pubmed:meshHeading |
pubmed-meshheading:7582362-Animals,
pubmed-meshheading:7582362-Disease Models, Animal,
pubmed-meshheading:7582362-Humans,
pubmed-meshheading:7582362-Inflammation,
pubmed-meshheading:7582362-Interleukin-6,
pubmed-meshheading:7582362-Multiple Organ Failure,
pubmed-meshheading:7582362-Neutrophils,
pubmed-meshheading:7582362-Platelet Activating Factor,
pubmed-meshheading:7582362-Rats,
pubmed-meshheading:7582362-Splanchnic Circulation
|
| pubmed:articleTitle |
Gut-derived mediators of multiple organ failure: platelet-activating factor and interleukin-6.
|
| pubmed:affiliation |
Department of Surgery, Denver General Hospital, University of Colorado Health Sciences Centre, Colorado 80204, USA.
|
| pubmed:publicationType |
Journal Article,
Review
|