Linked Life Data

7582325

Source:http://linkedlifedata.com/resource/pubmed/id/7582325

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-12-19
pubmed:abstractText
The negatively charged perfluorinated ionomer Nafion was used as a coating on hydrogen peroxide detecting platinum electrode as well as on a polycarbonate diffusion membrane in the construction of a glucose amperometric enzyme electrode. The current response of these electrodes to hydrogen peroxide, ascorbic acid, acetaminophen, uric acid and glucose was studied and the coating procedure was optimized. It was confirmed that the Nafion coating prevents interference by anionic substances such as ascorbic acid and uric acid, and decreases acetaminophen interference. In this regard it was shown that coating the glucose diffusion membrane (polycarbonate) was more effective than coating the platinum wire itself, because of the prevention of the homogeneous redox reaction of the interference species with hydrogen peroxide, as well as the additional diffusional resistance to the glucose flux. The glucose levels in serum samples were estimated and the stability of the enzyme electrodes during continuous operation in serum was studied. An enzyme electrode with constant sensitivity of ca. 1 microA/mM and a linear range of up to 15 mM, unaffected by contact with serum, is reported.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1350-4533
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
416-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effect of interference on the performance of glucose enzyme electrodes using Nafion coatings.
pubmed:affiliation
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque 87131, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't