| pubmed-article:7578884 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0229664 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C1101536 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0151449 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C1333196 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:7578884 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:7578884 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7578884 | pubmed:dateCreated | 1995-12-13 | lld:pubmed |
| pubmed-article:7578884 | pubmed:abstractText | We studied mononuclear cell subsets in 17 patients with primary Sjögren's syndrome (PSS) and in 11 normal controls by flow cytometry. We found a decreased percentage of CD4+ cells (p = 0.027) and a higher percentage of CD8+ cells in patients as compared to controls. In both, CD4+ cells and CD8+ cells, CD25 antigen was overexpressed (p = 0.005 and p = 0.025, respectively as compared to controls). We then measured spontaneous mRNA cytokine expression by T cells from 7 PSS patients and 5 normal controls by coupled reverse transcription-polymerase chain reaction. We found spontaneous mRNA expression for IFN-gamma, IL-10, IL-13 as well as for CD25. Our results suggest an overall T cell activation in PSS patients and provides evidence of a T cell cytokine regulatory imbalance which may play a role in the pathogenesis of this disease. | lld:pubmed |
| pubmed-article:7578884 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7578884 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7578884 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7578884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7578884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7578884 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7578884 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7578884 | pubmed:issn | 0891-6934 | lld:pubmed |
| pubmed-article:7578884 | pubmed:author | pubmed-author:LlorenteLL | lld:pubmed |
| pubmed-article:7578884 | pubmed:author | pubmed-author:Alcocer-Varel... | lld:pubmed |
| pubmed-article:7578884 | pubmed:author | pubmed-author:VillarrealG... | lld:pubmed |
| pubmed-article:7578884 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7578884 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:7578884 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7578884 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7578884 | pubmed:pagination | 223-9 | lld:pubmed |
| pubmed-article:7578884 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:meshHeading | pubmed-meshheading:7578884-... | lld:pubmed |
| pubmed-article:7578884 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7578884 | pubmed:articleTitle | Cytokine gene and CD25 antigen expression by peripheral blood T cells from patients with primary Sjögren's syndrome. | lld:pubmed |
| pubmed-article:7578884 | pubmed:affiliation | Department of Immunology and Rheumatology, Instituto Nacional de la Nutrición Salvador Zubirán, Tlalpan, México, D.F. | lld:pubmed |
| pubmed-article:7578884 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7578884 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
