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pubmed-article:7578211pubmed:abstractTextRecent studies have shown that the NADPH oxidase participates in the generation of superoxide anion in non-phagocytic cells. Here we report the isolation and nucleotide sequence of a cDNA for the cytochrome b-558 alpha-subunit of the NADPH oxidase in rat vascular smooth muscle cells (VSMCs). The coding region of the cDNA was 93% homologous to mouse and 81% to human in nucleotide sequence and 96% homologous to mouse and 89% to human in the deduced amino acid sequence. Our results provide a tool with which to explore the mechanism of superoxide anion generation in rat VSMCs and other non-phagocytic cells.lld:pubmed
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pubmed-article:7578211pubmed:articleTitleCytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells.lld:pubmed
pubmed-article:7578211pubmed:affiliationDepartment of Medicine, Emory University, Atlanta, GA 30322, USA.lld:pubmed
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pubmed-article:7578211pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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