rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1995-11-9
|
pubmed:abstractText |
The liver plays a central role in the whole organism's response to injury. Expression of hepatic acute-phase and heat-shock genes likely contributes to the restoration of homeostasis after stressful events. However, after prolonged ischemia, hepatic transcription of heat-shock genes can exclude the simultaneous transcription of acute-phase genes. The issue of whether hepatic 72-kd heat-shock protein (hsp72) gene expression is induced under perioperative conditions that do not result in prolonged liver ischemia and whether this might further affect the expression of the acute-phase reactant inter-alpha-trypsin inhibitor (alpha-Ti) was examined.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0003-3022
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
850-9
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7574066-Abdomen,
pubmed-meshheading:7574066-Acute-Phase Proteins,
pubmed-meshheading:7574066-Alpha-Globulins,
pubmed-meshheading:7574066-Anesthesia, General,
pubmed-meshheading:7574066-Animals,
pubmed-meshheading:7574066-Female,
pubmed-meshheading:7574066-Gene Expression Regulation,
pubmed-meshheading:7574066-HSP72 Heat-Shock Proteins,
pubmed-meshheading:7574066-Heat-Shock Proteins,
pubmed-meshheading:7574066-Liver,
pubmed-meshheading:7574066-RNA, Messenger,
pubmed-meshheading:7574066-Swine,
pubmed-meshheading:7574066-Trypsin Inhibitors
|
pubmed:year |
1995
|
pubmed:articleTitle |
Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig.
|
pubmed:affiliation |
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins, Medical Institutions, Baltimore, Maryland, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|