Linked Life Data

7572130

Source:http://linkedlifedata.com/resource/pubmed/id/7572130

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-11-14
pubmed:abstractText
Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustachian tube to open (POL = pressure opening level) under physiological conditions in laboratory mini pigs and under the influence of an i.v. organophosphorus compound (Paraoxon). The median POL in the untreated animals was 6.4 kPa (n = 8). After intoxication with Paraoxon the median POL increased to 12.0 kPa (n = 8). Tubal instillation of surfactant in intoxicated pigs reduced the POL to a median of 7.3 kPa (n = 8), while in non-intoxicated animals (n = 4) it also lowered the POL, though not significantly. These results suggest that organophosphorus compound interferes with the surfactant-dependent tubal patency.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0001-6489
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
528-31
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The influence of an insecticide on the function of the eustachian tube.
pubmed:affiliation
Department of Otorhinolaryngology, Faculty of Clinical Medicine, Mannheim, University of Heidelberg, Germany.
pubmed:publicationType
Journal Article