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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0020792,
umls-concept:C0024779,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0086418,
umls-concept:C0162775,
umls-concept:C0521390,
umls-concept:C0597357,
umls-concept:C0599668,
umls-concept:C1413402,
umls-concept:C1521699,
umls-concept:C1708726,
umls-concept:C1979845
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pubmed:issue |
2
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|
pubmed:dateCreated |
1995-10-23
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|
pubmed:databankReference |
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pubmed:abstractText |
We have identified a cosmid, at the D8S131 locus, that shows sequence homology with exon 2 of the rat gene for the neuronal nicotinic acetylcholine receptor alpha 2 subunit. A 357-bp sequence surrounding a rare cutter AscI site contains a 152-bp region of homology. The human CHRNA2 gene is therefore positioned at the D8S131 locus, which has been mapped to 8p21.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0740-7750
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|
pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
21
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7570187-Amino Acid Sequence,
pubmed-meshheading:7570187-Animals,
pubmed-meshheading:7570187-Base Sequence,
pubmed-meshheading:7570187-Chromosome Mapping,
pubmed-meshheading:7570187-Chromosomes, Human, Pair 8,
pubmed-meshheading:7570187-DNA,
pubmed-meshheading:7570187-DNA Primers,
pubmed-meshheading:7570187-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:7570187-Humans,
pubmed-meshheading:7570187-In Situ Hybridization, Fluorescence,
pubmed-meshheading:7570187-Neurons,
pubmed-meshheading:7570187-Polymerase Chain Reaction,
pubmed-meshheading:7570187-Rats,
pubmed-meshheading:7570187-Receptors, Nicotinic,
pubmed-meshheading:7570187-Sequence Homology, Amino Acid,
pubmed-meshheading:7570187-Sequence Homology, Nucleic Acid
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pubmed:year |
1995
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pubmed:articleTitle |
Identification of the human neuronal nicotinic cholinergic alpha 2 receptor locus, (CHRNA2), within an 8p21 mapped locus, by sequence homology with rat DNA.
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pubmed:affiliation |
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
