Linked Life Data

7569903

Source:http://linkedlifedata.com/resource/pubmed/id/7569903

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5231
pubmed:dateCreated
1995-10-25
pubmed:abstractText
Developmental changes in rat hippocampal transmitter release and synaptic plasticity were investigated. Recordings from pairs of pyramidal neurons in slices showed that an action potential in a CA3 neuron released only a single quantum of transmitter onto a CA1 neuron. Failures of synaptic transmission reflected probabilistic transmitter release. The probability of release (Pr) was 0.9 in 4- to 8-day-old rats and decreased to less than 0.5 at 2 to 3 weeks. Long-term potentiation (LTP) in 2- to 3-week-old rats was associated with an increase in Pr from a single synaptic site. The high initial Pr in 4- to 8-day-old rats normally occludes the expression of LTP at this stage.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
269
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1730-4
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Regulation of hippocampal transmitter release during development and long-term potentiation.
pubmed:affiliation
Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
pubmed:publicationType
Journal Article, In Vitro