Linked Life Data

7567119

Source:http://linkedlifedata.com/resource/pubmed/id/7567119

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-11-22
pubmed:abstractText
Fourier transform infrared spectroscopy (FT-IR) is an analysis method which over the spectral absorption, gives information about the molecular structures of systems. Recently, this method is widely used to the investigation of complex systems like cells and bacteria. Characteristic of FT-IR spectrum of bacteria depend closely to physiological and culture parameters. In this study, the infrared bands of intact bacteria are first tentatively attributed to the contribution of the cellular components. Secondly are compared the FT-IR spectra of Escherichia coli bacteria before and after treatment at sub-inhibitrice concentrations (< or = MIC) at penicillin A, penicillin G and nalidixic acid. The observed spectral perturbations are closely depending on the antibiotic treatment and are observed even if bacterial cell mass is far away from cell death. On the other hand, this spectral changes are related to the known mode of action of the used antibiotic.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0369-8114
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
300-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
FT-IR spectroscopy study of perturbations induced by antibiotic on bacteria (Escherichia coli).
pubmed:affiliation
Laboratoire de Spectroscopie Biomoléculaire, UFR de Pharmacie, Reims, France.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro