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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
1995-11-21
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pubmed:abstractText |
Patients with isolated vitamin E deficiency have an impaired ability to incorporate alpha-tocopherol into lipoproteins in the liver and usually have symptoms and signs of spinocerebellar dysfunction before adolescence. Accumulated evidence suggests that the alpha-tocopherol-transfer protein, which is presumed to function in the intracellular transport of alpha-tocopherol, is abnormal in these patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0028-4793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
333
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1313-8
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:7566022-Adult,
pubmed-meshheading:7566022-Aged,
pubmed-meshheading:7566022-Aged, 80 and over,
pubmed-meshheading:7566022-Base Sequence,
pubmed-meshheading:7566022-Carrier Proteins,
pubmed-meshheading:7566022-Female,
pubmed-meshheading:7566022-Heterozygote,
pubmed-meshheading:7566022-Humans,
pubmed-meshheading:7566022-Male,
pubmed-meshheading:7566022-Middle Aged,
pubmed-meshheading:7566022-Molecular Sequence Data,
pubmed-meshheading:7566022-Point Mutation,
pubmed-meshheading:7566022-Polymorphism, Genetic,
pubmed-meshheading:7566022-Spinocerebellar Degenerations,
pubmed-meshheading:7566022-Vitamin E,
pubmed-meshheading:7566022-Vitamin E Deficiency
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pubmed:year |
1995
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pubmed:articleTitle |
Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein.
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pubmed:affiliation |
Third Department of Internal Medicine, Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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